Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness

Background: Tight junction (TJ) disruption and dysfunction are involved in the progression of arteriosclerosis. miR-501-3p regulates endothelial TJ protein-1, resulting in TJ disruption. Because exosomal microRNAs can travel to distant tissues and influence cell behavior, patients with elevated miR-...

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Pubblicato in:Circ Rep
Autori principali: Toyama, Kensuke, Igase, Michiya, Spin, Joshua M., Abe, Yasunori, Javkhlant, Amarsanaa, Okada, Yoko, Wagenhäuser, Markus U., Schelzig, Hubert, Tsao, Philip S., Mogi, Masaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Japanese Circulation Society 2021
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956882/
https://ncbi.nlm.nih.gov/pubmed/33738350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1253/circrep.CR-20-0135
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