Type and Gene Location of KIT Mutations Predict Progression-Free Survival to First-Line Imatinib in Gastrointestinal Stromal Tumors: A Look into the Exon

SIMPLE SUMMARY: Although effective in the majority of patients, the progression-free survival (PFS) to imatinib treatment can vary widely in effectiveness. Based on the known predictive role of tyrosine kinase (KIT) and platelet-derived growth factor receptor α (PDGRA) tumor genotypes, the different...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Incorvaia, Lorena, Fanale, Daniele, Vincenzi, Bruno, De Luca, Ida, Bartolotta, Tommaso Vincenzo, Cannella, Roberto, Pantuso, Gianni, Cabibi, Daniela, Russo, Antonio, Bazan, Viviana, Badalamenti, Giuseppe
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956844/
https://ncbi.nlm.nih.gov/pubmed/33673554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13050993
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