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Whole Blood Thromboelastometry by ROTEM and Thrombin Generation by Genesia According to the Genotype and Clinical Phenotype in Congenital Fibrinogen Disorders

The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assays fail to predict the clinical phenotype. We aimed to assess the pheno- and genotypic associations of thrombin generation (TG) and ROTEM in CFD. We measured fibrinogen (Fg) activity and antigen, prot...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Szanto, Timea, Lassila, Riitta, Lemponen, Marja, Lehtinen, Elina, Neerman-Arbez, Marguerite, Casini, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956597/
https://ncbi.nlm.nih.gov/pubmed/33668986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052286
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