Vaccine Increases the Diversity and Activation of Intratumoral T Cells in the Context of Combination Immunotherapy

SIMPLE SUMMARY: Innovative strategies to reduce immune suppression and activate tumor-specific immunity are needed to help patients who do not respond or become resistant to immune checkpoint blockade therapies. In this study, we demonstrate that the addition of a cancer vaccine targeting a tumor-as...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Horn, Lucas A., Fousek, Kristen, Hamilton, Duane H., Hodge, James W., Zebala, John A., Maeda, Dean Y., Schlom, Jeffrey, Palena, Claudia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956439/
https://ncbi.nlm.nih.gov/pubmed/33669155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13050968
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