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Time-Resolved scRNA-Seq Tracks the Adaptation of a Sensitive MCL Cell Line to Ibrutinib Treatment

Since the approval of ibrutinib for relapsed/refractory mantle cell lymphoma (MCL), the treatment of this rare mature B-cell neoplasm has taken a great leap forward. Despite promising efficacy of the Bruton tyrosine kinase inhibitor, resistance arises inevitably and the underlying mechanisms remain...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fuhr, Viktoria, Vafadarnejad, Ehsan, Dietrich, Oliver, Arampatzi, Panagiota, Riedel, Angela, Saliba, Antoine-Emmanuel, Rosenwald, Andreas, Rauert-Wunderlich, Hilka
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956352/
https://ncbi.nlm.nih.gov/pubmed/33668876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052276
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