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Hepatitis B Virus-Like Particle: Targeted Delivery of Plasmid Expressing Short Hairpin RNA for Silencing the Bcl-2 Gene in Cervical Cancer Cells

Gene therapy research has advanced to clinical trials, but it is hampered by unstable nucleic acids packaged inside carriers and there is a lack of specificity towards targeted sites in the body. This study aims to address gene therapy limitations by encapsidating a plasmid synthesizing a short hair...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Akwiditya, Made Angga, Yong, Chean Yeah, Yusof, Mohd Termizi, Mariatulqabtiah, Abdul Razak, Ho, Kok Lian, Tan, Wen Siang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956328/
https://ncbi.nlm.nih.gov/pubmed/33652577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052320
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