Phage-Display Based Discovery and Characterization of Peptide Ligands against WDR5

WD40 is a ubiquitous domain presented in at least 361 human proteins and acts as scaffold to form protein complexes. Among them, WDR5 protein is an important mediator in several protein complexes to exert its functions in histone modification and chromatin remodeling. Therefore, it was considered as...

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Veröffentlicht in:Molecules
Hauptverfasser: Cao, Jiawen, Fan, Tiantian, Li, Yanlian, Du, Zhiyan, Chen, Lin, Wang, Ying, Wang, Xin, Shen, Jingkang, Huang, Xun, Xiong, Bing, Cao, Danyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956166/
https://ncbi.nlm.nih.gov/pubmed/33668971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051225
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