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DCC gene network in the prefrontal cortex is associated with total brain volume in childhood

BACKGROUND: Genetic variation in the guidance cue DCC gene is linked to psychopathologies involving dysfunction in the prefrontal cortex. We created an expression-based polygenic risk score (ePRS) based on the DCC coexpression gene network in the prefrontal cortex, hypothesizing that it would be ass...

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Vydáno v:J Psychiatry Neurosci
Hlavní autoři: Morgunova, Alice, Pokhvisneva, Irina, Nolvi, Saara, Entringer, Sonja, Wadhwa, Pathik, Gilmore, John, Styner, Martin, Buss, Claudia, Sassi, Roberto Britto, Hall, Geoffrey B.C., O’Donnell, Kieran J., Meaney, Michael J., Silveira, Patricia P., Flores, Cecilia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Joule Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955849/
https://ncbi.nlm.nih.gov/pubmed/33206040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.200081
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