11β-Hydroxylase (CYP11B1) gene variants and new-onset depression in later life

BACKGROUND: Cumulative exposure to high glucocorticoid levels is detrimental for the brain and may have particular implications in later life. A feature of late-life depression is increased cortisol secretion. Variants in the CYP11B1 gene, which codes for the enzyme responsible for cortisol synthesi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Psychiatry Neurosci
Prif Awduron: Ancelin, Marie-Laure, Norton, Joanna, Ritchie, Karen, Chaudieu, Isabelle, Ryan, Joanne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Joule Inc. 2021
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955840/
https://ncbi.nlm.nih.gov/pubmed/33245660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.190177
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