Fluid proteomics of CSF and serum reveal important neuroinflammatory proteins in blood–brain barrier disruption and outcome prediction following severe traumatic brain injury: a prospective, observational study

BACKGROUND: Severe traumatic brain injury (TBI) is associated with blood–brain barrier (BBB) disruption and a subsequent neuroinflammatory process. We aimed to perform a multiplex screening of brain enriched and inflammatory proteins in blood and cerebrospinal fluid (CSF) in order to study their rol...

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Veröffentlicht in:Crit Care
Hauptverfasser: Lindblad, Caroline, Pin, Elisa, Just, David, Al Nimer, Faiez, Nilsson, Peter, Bellander, Bo-Michael, Svensson, Mikael, Piehl, Fredrik, Thelin, Eric Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955664/
https://ncbi.nlm.nih.gov/pubmed/33712077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-021-03503-x
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