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Gasdermin D Influence Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway

BACKGROUND: The inflammation and apoptosis of podocytes contribute to the pathological progression of diabetic nephropathy. Gasdermin D (GSDMD) plays an executive role in pyroptosis, but its effect on high-glucose (HG)-induced inflammation and apoptosis remains unclear. The aim of this study was to...

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Publicado en:Med Sci Monit
Main Authors: Li, Huifang, Zhao, Kunxiao, Li, Ying
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955578/
https://ncbi.nlm.nih.gov/pubmed/33690262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.928411
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