Periadventitial Delivery of Simvastatin‐Loaded Microparticles Attenuate Venous Neointimal Hyperplasia Associated With Arteriovenous Fistula

BACKGROUND: Venous neointimal hyperplasia and venous stenosis (VS) formation can result in a decrease in arteriovenous fistula (AVF) patency in patients with end‐stage renal disease. There are limited therapies that prevent VNH/VS. Systemic delivery of simvastatin has been shown to reduce VNH/VS but...

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Bibliographic Details
Published in:J Am Heart Assoc
Main Authors: Zhao, Chenglei, Zuckerman, Sean T., Cai, Chuanqi, Kilari, Sreenivasulu, Singh, Avishek, Simeon, Michael, von Recum, Horst A., Korley, Julius N., Misra, Sanjay
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955373/
https://ncbi.nlm.nih.gov/pubmed/33283594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018418
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