Effects of High Fat Versus Normal Diet on Extracellular Vesicle–Induced Angiogenesis in a Swine Model of Chronic Myocardial Ischemia

BACKGROUND: Mesenchymal stem cell–derived extracellular vesicles (EVs) promote angiogenesis in the ischemic myocardium. This study examines the difference in vascular density, myocardial perfusion, molecular signaling, and gene expression between normal diet (ND) and high fat diet (HFD) groups at ba...

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Pubblicato in:J Am Heart Assoc
Autori principali: Aboulgheit, Ahmed, Potz, Brittany A., Scrimgeour, Laura A., Karbasiafshar, Catherine, Shi, Guangbin, Zhang, Zhiqi, Machan, Jason T., Schorl, Christoph, Brodsky, Alexander S., Braga, Karla, Pfeiffer, Melissa, Gao, May, Cummings, Olivia, Sodha, Neel R., Abid, M. Ruhul, Sellke, Frank W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955347/
https://ncbi.nlm.nih.gov/pubmed/33559477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.017437
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