Patients With LDLR and PCSK9 Gene Variants Experienced Higher Incidence of Cardiovascular Outcomes in Heterozygous Familial Hypercholesterolemia

BACKGROUND: Patients with familial hypercholesterolemia who harbored both low‐density lipoprotein receptor (LDLR) and PCSK9 (proprotein convertase subtilisin/kexin type 9) gene variants exhibit severe phenotype associated with substantially high levels of low‐density lipoprotein cholesterol. In this...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Doi, Takahito, Hori, Mika, Harada‐Shiba, Mariko, Kataoka, Yu, Onozuka, Daisuke, Nishimura, Kunihiro, Nishikawa, Ryo, Tsuda, Kosuke, Ogura, Masatsune, Son, Cheol, Miyamoto, Yoshihiro, Noguchi, Teruo, Shimokawa, Hiroaki, Yasuda, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955325/
https://ncbi.nlm.nih.gov/pubmed/33533259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.018263
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