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Structural and functional characterization of a putative de novo gene in Drosophila

Comparative genomic studies have repeatedly shown that new protein-coding genes can emerge de novo from noncoding DNA. Still unknown is how and when the structures of encoded de novo proteins emerge and evolve. Combining biochemical, genetic and evolutionary analyses, we elucidate the function and s...

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Publicat a:Nat Commun
Autors principals: Lange, Andreas, Patel, Prajal H., Heames, Brennen, Damry, Adam M., Saenger, Thorsten, Jackson, Colin J., Findlay, Geoffrey D., Bornberg-Bauer, Erich
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954818/
https://ncbi.nlm.nih.gov/pubmed/33712569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21667-6
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