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Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3

Epithelial cells organize an ordered array of non-centrosomal microtubules, the minus ends of which are regulated by CAMSAP3. The role of these microtubules in epithelial functions, however, is poorly understood. Here, we show that the kidneys of mice in which Camsap3 is mutated develop cysts at the...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Mitsuhata, Yuto, Abe, Takaya, Misaki, Kazuyo, Nakajima, Yuna, Kiriya, Keita, Kawasaki, Miwa, Kiyonari, Hiroshi, Takeichi, Masatoshi, Toya, Mika, Sato, Masamitsu
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954811/
https://ncbi.nlm.nih.gov/pubmed/33712686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85416-x
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