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Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3
Epithelial cells organize an ordered array of non-centrosomal microtubules, the minus ends of which are regulated by CAMSAP3. The role of these microtubules in epithelial functions, however, is poorly understood. Here, we show that the kidneys of mice in which Camsap3 is mutated develop cysts at the...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954811/ https://ncbi.nlm.nih.gov/pubmed/33712686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85416-x |
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