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Therapeutic effectiveness of thalidomide in a patient with treatment-resistant restless legs syndrome
Recent developments in the genetics of restless legs syndrome (RLS) revealed associations of disease risk with genetic loci containing the genes coding cereblon, the protein bound by thalidomide, and its endogenous substrate MEIS2, whose degradation is inhibited by the thalidomide-cereblon interacti...
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| Pubblicato in: | J Clin Sleep Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Academy of Sleep Medicine
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954015/ https://ncbi.nlm.nih.gov/pubmed/32729462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.8696 |
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