Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein

The dynamin GTPase is known to bundle actin filaments, but the underlying molecular mechanism and physiological relevance remain unclear. Our genetic analyses revealed a function of dynamin in propelling invasive membrane protrusions during myoblast fusion in vivo. Using biochemistry, total internal...

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Publicado no:Nat Cell Biol
Main Authors: Zhang, Ruihui, Lee, Donghoon M., Jimah, John R., Gerassimov, Nathalie, Yang, Changsong, Kim, Sangjoon, Luvsanjav, Delgermaa, Winkelman, Jonathan, Mettlen, Marcel, Abrams, Michael E., Kalia, Raghav, Keene, Peter, Pandey, Pratima, Ravaux, Benjamin, Kim, Ji Hoon, Ditlev, Jonathon A., Zhang, Guofeng, Rosen, Michael K., Frost, Adam, Alto, Neal M., Gardel, Margaret, Schmid, Sandra L., Svitkina, Tatyana M., Hinshaw, Jenny E., Chen, Elizabeth H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953826/
https://ncbi.nlm.nih.gov/pubmed/32451441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-0519-7
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