Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer

BACKGROUND: Contemporary deep learning approaches show cutting-edge performance in a variety of complex prediction tasks. Nonetheless, the application of deep learning in healthcare remains limited since deep learning methods are often considered as non-interpretable black-box models. However, the m...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Chereda, Hryhorii, Bleckmann, Annalen, Menck, Kerstin, Perera-Bel, Júlia, Stegmaier, Philip, Auer, Florian, Kramer, Frank, Leha, Andreas, Beißbarth, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953710/
https://ncbi.nlm.nih.gov/pubmed/33706810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00845-7
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