Responsiveness of human bronchial fibroblasts and epithelial cells from asthmatic and non-asthmatic donors to the transforming growth factor-β(1) in epithelial-mesenchymal trophic unit model

BACKGROUND: The asthma-related airway wall remodeling is associated i.a. with a damage of bronchial epithelium and subepithelial fibrosis. Functional interactions between human bronchial epithelial cells and human bronchial fibroblasts are known as the epithelial-mesenchymal trophic unit (EMTU) and...

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Udgivet i:BMC Mol Cell Biol
Main Authors: Paw, Milena, Wnuk, Dawid, Jakieła, Bogdan, Bochenek, Grażyna, Sładek, Krzysztof, Madeja, Zbigniew, Michalik, Marta
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953709/
https://ncbi.nlm.nih.gov/pubmed/33711932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-021-00356-8
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