Lineage-specific regulation of inducible and constitutive mast cells in allergic airway inflammation

Murine mast cells (MCs) contain two lineages: inducible bone marrow–derived mucosal MCs (MMCs) and constitutive embryonic-derived connective tissue MCs (CTMCs). Here, we use RNA sequencing, flow cytometry, and genetic deletion in two allergic lung inflammation models to define these two lineages. We...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Derakhshan, Tahereh, Samuchiwal, Sachin K., Hallen, Nils, Bankova, Lora G., Boyce, Joshua A., Barrett, Nora A., Austen, K. Frank, Dwyer, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Technical Advances and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953627/
https://ncbi.nlm.nih.gov/pubmed/32946563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200321
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