Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy

STUDY OBJECTIVES: Evaluate efficacy and safety of lower-sodium oxybate (LXB), a novel oxybate medication with 92% less sodium than sodium oxybate (SXB). METHODS: Adults aged 18–70 years with narcolepsy with cataplexy were eligible. The study included a ≤30-day screening period; a 12-week, open-label...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Bogan, Richard K, Thorpy, Michael J, Dauvilliers, Yves, Partinen, Markku, Del Rio Villegas, Rafael, Foldvary-Schaefer, Nancy, Skowronski, Roman, Tang, Lihua, Skobieranda, Franck, Šonka, Karel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Neurological Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953213/
https://ncbi.nlm.nih.gov/pubmed/33184650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsaa206
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