Interleukin-22 From Type 3 Innate Lymphoid Cells Aggravates Lupus Nephritis by Promoting Macrophage Infiltration in Lupus-Prone Mice

Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE). Our previous studies demonstrated increased serum and renal Interleukin (IL)-22 in LN patients and MRL/lpr mice. This study investigated the role of IL-22 and its mechanism in LN. Here, we found that...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Hu, Lingzhen, Hu, Jingyi, Chen, Liheng, Zhang, Yi, Wang, Qingqing, Yang, Xuyan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953152/
https://ncbi.nlm.nih.gov/pubmed/33717066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.584414
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