Influence of Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphism on High-Dose Methotrexate-Related Toxicities in Pediatric Non-Hodgkin Lymphoma Patients

PURPOSE: This retrospective study aimed to investigate the relationships between the methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C and high-dose methotrexate (HD-MTX)-related toxicities in pediatric non-Hodgkin lymphoma (NHL) patients. PATIENTS AND METHODS: We reviewed the medical records...

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Udgivet i:Front Oncol
Main Authors: Lu, Suying, Zhu, Xiaoqin, Li, Wei, Chen, Huimou, Zhou, Dalei, Zhen, Zijun, Sun, Feifei, Huang, Junting, Zhu, Jia, Wang, Juan, Zhang, Yizhuo, Sun, Xiaofei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953141/
https://ncbi.nlm.nih.gov/pubmed/33718146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.598226
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