Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

An effective vaccine to prevent HIV transmission has not yet been achieved. Modulation of the microbiome via probiotic therapy has been suggested to result in enhanced mucosal immunity. Here, we evaluated whether probiotic therapy could improve the immunogenicity and protective efficacy of SIV/HIV v...

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Pubblicato in:NPJ Vaccines
Autori principali: Klatt, Nichole R., Broedlow, Courtney, Osborn, Jessica M., Gustin, Andrew T., Dross, Sandra, O’Connor, Megan A., Coronado, Ernesto, Barnette, Philip, Hensley-McBain, Tiffany, Zevin, Alexander S., Muir, Roshell, Roederer, Alexander, Wangari, Solomon, Iwayama, Naoto, Ahrens, Chul Y., Smedley, Jeremy, Moats, Cassandra, Lynch, Rebecca M., Haddad, Elias K., Haigwood, Nancy L., Fuller, Deborah H., Manuzak, Jennifer A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952719/
https://ncbi.nlm.nih.gov/pubmed/33707443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-021-00298-4
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