RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane

The receptor for advanced glycation end-products (RAGE) and the G protein-coupled angiotensin II (AngII) type I receptor (AT1) play a central role in cardiovascular diseases. It was recently reported that RAGE modifies AngII-mediated AT1 activation via the membrane oligomeric complex of the two rece...

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Publicado no:Sci Rep
Main Authors: Yokoyama, Serina, Kawai, Tatsuo, Yamamoto, Koichi, Yibin, Huang, Yamamoto, Hiroko, Kakino, Akemi, Takeshita, Hikari, Nozato, Yoichi, Fujimoto, Taku, Hongyo, Kazuhiro, Takahashi, Toshimasa, Nakagami, Futoshi, Akasaka, Hiroshi, Takami, Yoichi, Takeya, Yasushi, Sugimoto, Ken, Sawamura, Tatsuya, Rakugi, Hiromi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952713/
https://ncbi.nlm.nih.gov/pubmed/33707701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-85312-4
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