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Pretreatment of Huoxue Jiedu Formula Ameliorates Myocardial Ischaemia/Reperfusion Injury by Decreasing Autophagy via Activation of the PI3K/AKT/mTOR Pathway

Background: Myocardial ischaemia/reperfusion (I/R) results in myocardial injury via excessive autophagy. Huoxue Jiedu Formula (HJF) has been widely applied in China for the treatment of ischaemic heart disease. However, the mechanisms of HJF are still poorly understood. Thus, the present experiment...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Long, Linzi, Yu, Zikai, Chen, ShengJun, Wu, Jiarui, Liu, Yingying, Peng, Jun, Qu, Hua, Fu, Changgeng
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952439/
https://ncbi.nlm.nih.gov/pubmed/33716739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.608790
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