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Non-ionotropic NMDA receptor signaling gates bidirectional structural plasticity of dendritic spines

Experience-dependent refinement of neuronal connections is critically important for brain development and learning. Here, we show that ion-flow-independent NMDA receptor (NMDAR) signaling is required for the long-term dendritic spine growth that is a vital component of brain circuit plasticity. We f...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Stein, Ivar S., Park, Deborah K., Claiborne, Nicole, Zito, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952241/
https://ncbi.nlm.nih.gov/pubmed/33503425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108664
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