Targeting radiation‒resistant prostate cancer stem cells by B7-H3 CAR T cells

Radiation therapy (RT) is a key treatment for prostate cancer (PCa). However, RT resistance can contribute to treatment failure. PCa stem cells (PCSCs) are radioresistant. We recently found that fractionated irradiation (FIR) preferentially upregulates expression of the immune checkpoint B7-H3 (CD27...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Zhang, Yida, He, Lile, Sadagopan, Ananthan, Ma, Tao, Dotti, Gianpietro, Wang, Yufeng, Zheng, Hui, Gao, Xin, Wang, Dian, DeLeo, Albert B., Fan, Song, Sun, Ruochuan, Yu, Ling, Zhang, Liyuan, Wang, Gongxian, Ferrone, Soldano, Wang, Xinhui
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952034/
https://ncbi.nlm.nih.gov/pubmed/33653946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0446
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