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Public Baseline and shared response structures support the theory of antibody repertoire functional commonality

The naïve antibody/B-cell receptor (BCR) repertoires of different individuals ought to exhibit significant functional commonality, given that most pathogens trigger an effective antibody response to immunodominant epitopes. Sequence-based repertoire analysis has so far offered little evidence for th...

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Dades bibliogràfiques
Publicat a:PLoS Comput Biol
Autors principals: Raybould, Matthew I. J., Marks, Claire, Kovaltsuk, Aleksandr, Lewis, Alan P., Shi, Jiye, Deane, Charlotte M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951972/
https://ncbi.nlm.nih.gov/pubmed/33647011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008781
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