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Induction of MMP‐1, MMP‐3 and TIMP‐1 in normal dermal fibroblasts by chronic venous leg ulcer wound fluid

In the wound bed of chronic venous leg ulcers, an imbalance of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) may cause excessive proteolysis and impair wound granulation. Soluble mediators in the wound environment may be responsible for this imbalance. The in vi...

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Publicat a:Int Wound J
Autors principals: Subramaniam, Kavitha, Pech, Cheryl M, Stacey, Michael C, Wallace, Hilary J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951760/
https://ncbi.nlm.nih.gov/pubmed/18336381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-481X.2007.00336.x
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