Plasma metabolomics of presymptomatic PSEN1‐H163Y mutation carriers: a pilot study

BACKGROUND AND OBJECTIVE: PSEN1‐H163Y carriers, at the presymptomatic stage, have reduced (18)FDG‐PET binding in the cerebrum of the brain (Scholl et al., Neurobiol Aging 32:1388–1399, 2011). This could imply dysfunctional energy metabolism in the brain. In this study, plasma of presymptomatic PSEN1...

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Detaylı Bibliyografya
Yayımlandı:Ann Clin Transl Neurol
Asıl Yazarlar: Natarajan, Karthick, Ullgren, Abbe, Khoshnood, Behzad, Johansson, Charlotte, Laffita‐Mesa, José M., Pannee, Josef, Zetterberg, Henrik, Blennow, Kaj, Graff, Caroline
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951103/
https://ncbi.nlm.nih.gov/pubmed/33476461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51296
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