Peripheral synucleinopathy in Parkinson disease with LRRK2 G2385R variants

OBJECTIVE: Recent studies demonstrated cutaneous phosphorylated α synuclein (p‐syn) deposition in idiopathic and some monogenetic Parkinson disease (PD) patients, suggesting synucleinopathy identical to that in the brain. Although the LRRK2 Gly2385Arg (G2385R) variant is a common PD risk factor in t...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Yang, Jing, Wang, Hao, Yuan, Yanpeng, Fan, Shiheng, Li, Lanjun, Jiang, Chenyang, Mao, Chengyuan, Shi, Changhe, Xu, Yuming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951097/
https://ncbi.nlm.nih.gov/pubmed/33527742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51301
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