A general method for quantifying ligand binding to unmodified receptors using Gaussia luciferase

Reliable measurement of ligand binding to cell surface receptors is of outstanding biological and pharmacological importance. Resonance energy transfer–based assays are powerful approaches to achieve this goal, but the currently available methods are hindered by the necessity of receptor tagging, wh...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Tóth, András Dávid, Garger, Dániel, Prokop, Susanne, Soltész-Katona, Eszter, Várnai, Péter, Balla, András, Turu, Gábor, Hunyady, László
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950324/
https://ncbi.nlm.nih.gov/pubmed/33545176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100366
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