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ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29

Birdshot Uveitis (BU) is a blinding inflammatory eye condition that only affects HLA-A29-positive individuals. Genetic association studies linked ERAP2 with BU, an aminopeptidase which trims peptides before their presentation by HLA class I at the cell surface, which suggests that ERAP2-dependent pe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Venema, Wouter J., Hiddingh, Sanne, de Boer, Joke H., Claas, Frans H. J., Mulder, Arend, den Hollander, Anneke I., Stratikos, Efstratios, Sarkizova, Siranush, van der Veken, Lars T., Janssen, George M. C., van Veelen, Peter A., Kuiper, Jonas J. W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7950316/
https://ncbi.nlm.nih.gov/pubmed/33717175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.634441
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