Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer

BACKGROUND: Neoadjuvant chemoradiation therapy (CRT) is a widely used preoperative treatment strategy for locally advanced rectal cancer (LARC). However, a few studies have evaluated the molecular changes caused by neoadjuvant CRT in these cancer tissues. Here, we aimed to investigate changes in imm...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Seo, Incheol, Lee, Hye Won, Byun, Sang Jun, Park, Jee Young, Min, Hyeonji, Lee, Sung Hwan, Lee, Ju-Seog, Kim, Shin, Bae, Sung Uk
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Immunotherapy Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949478/
https://ncbi.nlm.nih.gov/pubmed/33692216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001610
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