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Heat shock transcription factor 1 is SUMOylated in the activated trimeric state

The heat shock response is a transcriptional program of organisms to counteract an imbalance in protein homeostasis. It is orchestrated in all eukaryotic cells by heat shock transcription factor 1 (Hsf1). Despite very intensive research, the intricacies of the Hsf1 activation-attenuation cycle remai...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Kmiecik, Szymon W., Drzewicka, Katarzyna, Melchior, Frauke, Mayer, Matthias P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949154/
https://ncbi.nlm.nih.gov/pubmed/33493517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100324
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