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Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner
Mitochondrial DNA is located in organelle that house essential metabolic reactions and contains high reactive oxygen species. Therefore, mitochondrial DNA suffers more oxidative damage than its nuclear counterpart. Formation of a repair enzyme complex is beneficial to DNA repair. Recent studies have...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7949115/ https://ncbi.nlm.nih.gov/pubmed/33482196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100309 |
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