An “epitomic” analysis of the specificity of conformation-dependent, anti-Aß amyloid monoclonal antibodies

Antibodies against Aß amyloid are indispensable research tools and potential therapeutics for Alzheimer’s disease. They display several unusual properties, such as specificity for aggregated forms of the peptide, the ability to distinguish polymorphic aggregate structures, and the ability to recogni...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Reyes-Ruiz, Jorge Mauricio, Nakajima, Rie, Baghallab, Ibtisam, Goldschmidt, Luki, Sosna, Justyna, Mai Ho, Phuong Nguyen, Kumosani, Taha, Felgner, Philip L., Glabe, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949048/
https://ncbi.nlm.nih.gov/pubmed/33298522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015501
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