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Zinc transporter mutations linked to acrodermatitis enteropathica disrupt function and cause mistrafficking
ZIP4 is a representative member of the Zrt-/Irt-like protein (ZIP) transporter family and responsible for zinc uptake from diet. Loss-of-function mutations of human ZIP4 (hZIP4) drastically reduce zinc absorption, causing a life-threatening autosomal recessive disorder, acrodermatitis enteropathica...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7949036/ https://ncbi.nlm.nih.gov/pubmed/33837739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100269 |
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