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DNA damage promotes ER stress resistance through elevation of unsaturated phosphatidylcholine in Caenorhabditis elegans

DNA damage triggers the cellular adaptive response to arrest proliferation and repair DNA damage; when damage is too severe to be repaired, apoptosis is initiated to prevent the spread of genomic insults. However, how cells endure DNA damage to maintain cell function remains largely unexplored. By u...

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Publicado en:J Biol Chem
Autores principales: Deng, Jianhui, Bai, Xue, Tang, Haiqing, Pang, Shanshan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949029/
https://ncbi.nlm.nih.gov/pubmed/33208465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016083
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