Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity

Acetaminophen (APAP)-induced liver necrosis is a form of regulated cell death (RCD) in which APAP activates the mitogen-activated protein kinases (MAPKs) and specifically the c-Jun-N-terminal kinase (JNK) pathway, leading to necrotic cell death. Previously, we have shown that receptor interacting pr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Iorga, Andrea, Donovan, Katherine, Shojaie, Layla, Johnson, Heather, Kwok, Janet, Suda, Jo, Lee, Brian T., Aghajan, Mariam, Shao, Ling, Liu, Zhang-Xu, Dara, Lily
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948960/
https://ncbi.nlm.nih.gov/pubmed/33460648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100300
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