Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple-negative breast cancer cells

Melatonin has been reported to induce effective reduction in growth and development in a variety of tumors, including breast cancer. In triple-negative breast cancer (TNBC) cells, melatonin attenuates a variety of cancer features, such as tumor growth and apoptosis resistance, through a number of st...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Jardin, Isaac, Diez-Bello, Raquel, Falcon, Debora, Alvarado, Sandra, Regodon, Sergio, Salido, Gines M., Smani, Tarik, Rosado, Juan A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948746/
https://ncbi.nlm.nih.gov/pubmed/33380424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015769
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