Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19

BACKGROUND: Air pollution exposure and idiopathic pulmonary fibrosis (IPF) cause a poor prognosis after SARS-CoV-2 infection, but the underlying mechanisms are not well explored. Angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) are the keys to the entry of SARS-Co...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Li, Hsin-Hsien, Liu, Chen-Chi, Hsu, Tien-Wei, Lin, Jiun-Han, Hsu, Jyuan-Wei, Li, Anna Fen-Yau, Yeh, Yi-Chen, Hung, Shih-Chieh, Hsu, Han-Shui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948665/
https://ncbi.nlm.nih.gov/pubmed/33706759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-021-00404-3
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