Volatile allosteric antagonists of mosquito odorant receptors inhibit human-host attraction

Odorant-dependent behaviors in insects are triggered by the binding of odorant ligands to the variable subunits of heteromeric olfactory receptors. Previous studies have shown, however, that specific odor binding to ORco, the common subunit of odorant receptor heteromers, may allosterically alter ol...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Kythreoti, Georgia, Sdralia, Nadia, Tsitoura, Panagiota, Papachristos, Dimitrios P., Michaelakis, Antonios, Karras, Vasileios, Ruel, David M., Yakir, Esther, Bohbot, Jonathan D., Schulz, Stefan, Iatrou, Kostas
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948460/
https://ncbi.nlm.nih.gov/pubmed/33298524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.016557
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