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Salivary complement inhibitors from mosquitoes: Structure and mechanism of action

Inhibition of the alternative pathway (AP) of complement by saliva from Anopheles mosquitoes facilitates feeding by blocking production of the anaphylatoxins C3a and C5a, which activate mast cells leading to plasma extravasation, pain, and itching. We have previously shown that albicin, a member of...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Strayer, Ethan C., Lu, Stephen, Ribeiro, Jose, Andersen, John F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948415/
https://ncbi.nlm.nih.gov/pubmed/33199367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015230
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