Gene expression signature predicts relapse in adult patients with cytogenetically normal acute myeloid leukemia

Although ∼80% of adult patients with cytogenetically normal acute myeloid leukemia (CN-AML) achieve a complete remission (CR), more than half of them relapse. Better identification of patients who are likely to relapse can help to inform clinical decisions. We performed RNA sequencing on pretreatmen...

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Pubblicato in:Blood Adv
Autori principali: Walker, Christopher J., Mrózek, Krzysztof, Ozer, Hatice Gulcin, Nicolet, Deedra, Kohlschmidt, Jessica, Papaioannou, Dimitrios, Genutis, Luke K., Bill, Marius, Powell, Bayard L., Uy, Geoffrey L., Kolitz, Jonathan E., Carroll, Andrew J., Stone, Richard M., Garzon, Ramiro, Byrd, John C., Eisfeld, Ann-Kathrin, de la Chapelle, Albert, Bloomfield, Clara D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948288/
https://ncbi.nlm.nih.gov/pubmed/33683341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003727
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