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Synthesis and Operating Optimization of the PEG Conjugate via CuAAC in scCO(2)

[Image: see text] A new sustainable green protocol for obtaining polyethylene glycol (PEG) conjugates, with a prototype molecule, which in this work was coumarin, by means of click chemistry is presented. The organic solvents commonly used for this type of reaction were replaced by supercritical car...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: López, Sonia, Gracia, Ignacio, García, María Teresa, Rodríguez, Juan Francisco, Ramos, María Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948234/
https://ncbi.nlm.nih.gov/pubmed/33718707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c05466
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