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Multicellular Systems to Translate Somatic Cell Genome Editors to Humans

As genome editors move into clinical trials, there is a need to establish ex vivo multicellular systems to rapidly assess and predict toxic effects of genome editors in physiologically relevant human models. Advancements in organoid and organs-on-chip technologies offer the possibility to create mul...

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Détails bibliographiques
Publié dans:Curr Opin Biomed Eng
Auteurs principaux: Hernandez-Gordillo, Victor, Casolaro, Thomas Caleb, Ebrahimkhani, Mo R, Kiani, Samira
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948211/
https://ncbi.nlm.nih.gov/pubmed/33718690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2020.100249
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