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Nicotinic receptor modulation of primary afferent excitability with selective regulation of Aδ-mediated spinal actions

Somatosensory input strength can be modulated by primary afferent depolarization (PAD) generated predominantly via presynaptic GABA(A) receptors on afferent terminals. We investigated whether ionotropic nicotinic acetylcholine receptors (nAChRs) also provide modulatory actions, focusing on myelinate...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurophysiol
Prif Awduron: Shreckengost, Jacob, Halder, Mallika, Mena-Avila, Elvia, Garcia-Ramirez, David Leonardo, Quevedo, Jorge, Hochman, Shawn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948147/
https://ncbi.nlm.nih.gov/pubmed/33326305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00228.2020
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